Socks and Shoes Go Hand in Hand
You've found your perfect shoe, now here's why you need the right sock!

A high quality run sock will:

• manage moisture
• protect the foot from shoe irration
• provide some impact protection

JUST SAY NO TO COTTON!   Why?  Cotton retains moisture and when you have moisture, heat, and friction  you are more likely to get blisters, calluses, and hot spots.  Also, cotton gets more abrasive when wet, all reasons to keep cotton out of your running shoe.

Blends of synthetic fibers like nylon, polyester, Lycra® Spandex, olefin, or CoolMax® are best for managing moisture build-up and are compatible with the materials inside your shoes.  Synthetics are "hydrophobic" meaning they don't like water so they pull the moisture away from the foot in a way that maximizes evaporation.

Natural fibers like wool, bamboo, and coconut also make great fitting, comfortable socks in addition to being a renewable resource unlike the petroleum based synthetics.
Wool has long been used in running socks because of its natural moisture management qualities, thermo regulation capabilities, as well as natural anti-microbial characteristics.  Potential itching that can sometimes be attributed to wool is now eliminated through advanced manufacturing processes.  

There are more features to look for in a premium running sock beside the fabric.  Hand-linked or seamless toe enclosures eliminate the chance of rubbing and irritation to the top of the toes. 
Power bands, arch supports, and articulated arches improve the fit of the sock by reducing unnecessary bulk and keep the sock from twisting in the shoe.